Initial dose of interferon alfa-2b
| Initial dose of interferon alfa-2b (U/day, 6 times per week) | Patents without diabetes mellitus (n=49) | Patients with diabetes mellitus (n=9) | |||||
|---|---|---|---|---|---|---|---|
| Retinopathy | Retinopathy | ||||||
| Absent (n=30) | Developed (n=19) | Absent (n=2) | Developed (n=7) | ||||
| 3 × 106 | 13 | 4 (23%) | 2 | 0 (0%) | |||
| 6 × 106 | 11 | 6 (35%) | 0 | 3 (100%) | |||
| 9 × 106 | 6 | 9 (60%) | 0 | 4 (100%) | |||
↵p<0.01, Kruskal–Wallis rank test, adapted from Hayasakaet al.42