Patient no | CMV extraocular | CD4+ | Induction therapy | Maintenance | Interval E-Oc/Ret | Survival | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Date | Localisation | ||||||||||||
1 | 01-06-91 | Upper GI | 20 | GCV(2)/Fosc(1)/GCV+Fosc(2) | GCV | 16 | 8 | ||||||
2 | 01-03-90 | Poly rad | 10 | GCV(1)/GCV + Fosc(2) | GCV | 11 | 2 | ||||||
3 | 10-07-91 | Upper GI | 40 | GCV(4) | GCV | — | 4 | ||||||
4 | 07-04-89 | Upper GI | 10 | GCV(2)/Fosc(2) | Fosc | 2 | 3 | ||||||
5 | 01-05-89 | Lower GI | 10 | GCV(3) | — | 3 | 2 | ||||||
6 | 01-07-92 | Lungs | 10 | GCV(3) | — | 2 | 2 | ||||||
7 | 15-03-95 | Upper GI | 10 | GCV(2) | — | 4 | 4 | ||||||
8 | 01-06-92 | Upper GI | 10 | GCV(4) | — | 5 | 1 | ||||||
9 | 15-09-92 | Upper GI | 10 | GCV(2) | — | 2 | 2 | ||||||
10 | 09-10-92 | Upper GI | 10 | GCV(2)/Fosc(2) | — | 6 | 6 | ||||||
11 | 01-06-90 | Upper GI | 40 | GCV(2) | — | 6 | 7 | ||||||
12 | 20-01-94 | Lower GI | 40 | GCV(3) | — | 9 | 3 | ||||||
13 | 01-04-93 | Lower GI | 10 | GCV(5) | — | 8 | 4 | ||||||
14 | 08-05-95 | Lower GI | 20 | Fosc(3) | — | 7 | 2 | ||||||
15 | 09-12-93 | Lower GI | 10 | GCV(2) | — | 11 | 5 | ||||||
16 | 20-08-92 | Lower GI | 10 | GCV(3)/Fosc(1) | — | 9 | 12 | ||||||
17 | 01-08-92 | Lower GI | 20 | GCV(3) | — | 2 | 8 | ||||||
18 | 01-02-91 | Lower GI | 20 | GCV(2) | — | 6 | 1 | ||||||
19 | 05-03-92 | Lungs | 10 | GCV(1)/Fosc(2) | — | — | 2 | ||||||
20 | 20-09-90 | Upper GI | 80 | GCV(2) | — | — | 11 |
Date=date of diagnosis of extraocular CMV disease. Localisation: upper GI=upper gastrointestinal tract; lower GI=lower gastrointestinal tract; Lungs=CMV pneumonitis; Poly rad=CMV polyradiculopathy; CD4+=CD4 positive lymphocyte count, cells ×106/l. Induction therapy: GCV=ganciclovir 5 mg/kg/twice daily; Fosc=foscavir 90 mg/kg/twice daily; GCV+ Fosc=combination of both therapies. (n) = number of weeks treated. Maintenance: GCV=ganciclovir 5 mg/kg/day; Fosc=foscavir 90 mg/kg/day. Interval E-Oc/Ret=time between extraocular CMV disease and CMV retinitis in months; (—) = no CMV retinitis occurred. Survival=survival time after diagnosis of CMV retinitis in months.