Comparison of patients at the time of uveitis onset compared with maximal levels in patients without uveitis
| Patients with uveitis (n=10) | Patients without uveitis (n=7) | p Value | |
|---|---|---|---|
| CD4+ T lymphocyte count (×106/l) | 103.1 (107.1) (n=10) | 61.4 (57.2) (n=5) | 0.44 |
| Change in CD4+ T lymphocyte count from baseline (×106/l) | 68.0 (76.1) (n=9) | 5.0 (10.6) (n=5) | 0.04 |
| Serum creatinine (mg/dl) | 1.20 (0.27) (n=10) | 1.20 (0.25) (n=7) | 1.0 |
| Change in serum creatinine from baseline (mg/dl) | 0.15 (0.10) (n=10) | 0.17 (0.19) (n=7) | 0.76 |
| Proteinuria | |||
| 0+ | 1 | 1 | 0.50 |
| Trace | 2 | 0 | |
| 1+ | 4 | 2 | |
| 2+ | 3 | 1 | |
| 3+ | 0 | 1 | |
| 4+ | 0 | 0 | |
| Vision (logMAR units) | 0.362 (0.230) (n=10) | 0.164 (0.148) (n=7) | 0.06 |
| Change in vision (logMAR units) | 0.247 (0.195) (n=9) | 0.0 (0.0) (n=7) | 0.005 |
| Intraocular pressure (mm Hg) | 7.8 (1.9) (n=9) | 9.0 (3.8) (n=5) | 0.43 |
| Change in intraocular pressure from baseline (mm Hg) | 4.9 (2.3) (n=7) | 3.6 (2.5) (n=5) | 0.39 |
↵Snellen visual acuity was recorded for the right eye in patients without uveitis or with bilateral uveitis, or the affected eye in patients with unilateral uveitis, and converted to logMAR units.11 12
↵Intraocular pressure (IOP) was recorded for the right eye in patients without uveitis or with bilateral uveitis, or the affected eye in patients with unilateral uveitis. For patients without uveitis, the least IOP measurement while on cidofovir therapy was used.