Before therapy (1) | 0.13 (0.03) | 0.12 (0.03) | 0.13 (0.04) | | 0.05 (0.02) | 0.05 (0.02) | 0.05 (0.02) | | 0.92 (0.27) | 1.03 (0.28) | 1.00 (0.34) |
After 6 months (2) | 0.13 (0.06) | 0.13 (0.05) | — | 0.05 (0.02) | 0.05 (0.03) | — | 1.10 (0.17) | 1.03 (0.22) | — |
After 12 months (3) | 0.11 (0.04) | 0.13 (0.03) | — | 0.04 (0.01) | 0.05 (0.03) | — | 1.06 (0.24) | 1.01 (0.26) | — |
After 24 months (4) | 0.1 (0.02) | 0.12 (0.03) | — | 0.03 (0.01) | 0.04 (0.02) | — | 1.38 (0.31) | 1.06 (0.29) | — |
Statistically significant | C to 1: not significant (p=0.89) | C to 1: not significant (p=0.94) | C to 1: not significant (p=0.53) |
in Wilcoxon's test | C to 2: not significant (p=0.91) | C to 2: not significant (p=0.73) | C to 2: not significant (p=0.44) |
(p=<0.05) | C to 3: not significant (p=0.22) | C to 3: not significant (p=0.16) | C to 3: not significant (p=0.67) |
| C to 4: not significant (p=0.08) |
C to 4: significant (p=0.007)
|
C to 4: significant (p=0.013) |
| C to P1: not significant (p=0.52) | C to P1: not significant (p=0.26) | C to P1: not significant (p=0.54) |
| C to P2: not significant (p=0.70) | C to P2: not significant (p=0.49) | C to P2: not significant (p=0.78) |
| C to P3: not significant (p=0.61) | C to P3: not significant (p=1.0) | C to P3: not significant (p=1.0) |
| C to P4: not significant (p=0.64) | C to P4: not significant (p=0.43) | C to P4: not significant (p=0.66) |