Subretinal fluid ofloxacin concentrations (μg/ml) in treatment groups
| Patient No | Topical ofloxacin | Patient No | Oral ofloxacin | Patient No | Topical+oral ofloxacin |
|---|---|---|---|---|---|
| 1 | 0.16 | 1 | 0.94 | 1 | 1.87 |
| 2 | 0.34 | 2 | 1.13 | 2 | 4.78 |
| 3 | 0.73 | 3 | 1.29 | 3 | 2.29 |
| 4 | 0.61 | 4 | 3.65 | 4 | 1.11 |
| 5 | 0.29 | 5 | 2.16 | 5 | 1.56 |
| 6 | 0.32 | 6 | 0.98 | 6 | 3.41 |
| 7 | 0.29 | 7 | 1.02 | 7 | 1.18 |
| 8 | 0.41 | 8 | 2.12 | 8 | 3.01 |
| 9 | 0.33 | 9 | 0.99 | 9 | 4.02 |
| 10 | 1.11 | 10 | 2.88 | ||
| 11 | 2.19 | 11 | 1.05 | ||
| Mean (SEM) | 0.39 (0.06) | Mean (SEM) | 1.60 (0.26) | Mean (SEM) | 2.47 (0.38) |
↵Two drops of 0.3% solution every 30 minutes for 3 hours and every 60 minutes for the next 3 hours before surgery.
↵A single dose 400 mg 8 hours before surgery.
↵A single dose 400 mg 8 hours before surgery and two drops of 0.3% solution every 30 minutes for 3 hours and every 60 minutes for the next 3 hours before surgery.