Patient No | Before HAART | After HAART | Last exam | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Exam 0 | Exam 1 | Exam 2 | Exam 3 | Exam 4 | Exam 5 | Exam 6 | Exam 7 | After n months | PCR | CD4+ | |||||||
CD4+ | PCR | CD4+ | PCR | PCR | PCR | CD4+ | PCR | PCR | PCR | CD4+ | PCR | ||||||
1 | 10 | 1469 | 70 | — | — | — | 110 | — | — | — | 230 | — | 18 | — | 130 | ||
2 | 150 | 914 | 150 | — | — | — | 140 | — | — | — | 180 | — | 18 | — | 150 | ||
3 | 20 | 1136 | 210 | — | — | — | 250 | — | — | — | 250 | — | 12 | — | 170 | ||
4 | 20 | 562 | 90 | — | — | — | 220 | — | — | — | ND | — | 9 | — | 460 | ||
5 | 40 | 1529 | 160 | — | — | — | 130 | — | — | 171 | 140 | — | 18 | — | 170 | ||
6 | 40 | 382 | 30 | 2071 | 1474 | ND | ND | ND | ND | ND | 100 | — | 12 | — | 100 | ||
7 | 40 | 2355 | 100 | — | — | 376 | 150 | 584 | — | — | 170 | — | 16# | — | 180 | ||
8 | 90 | 1259 | 170 | 384 | — | — | 200 | — | — | — | 190 | — | 22 | — | 200 | ||
9* | 30 | 1423 | 90 | — | — | 947 | 100 | — | ND | ND | ND | ND | 13 | — | 100 | ||
10* | 20 | 604 | 140 | 133 | — | — | 200 | — | — | — | 200 | — | 16 | — | 200 | ||
11 | 30 | — | 10 | — | — | 237 | ND | ND | — | — | ND | ND | 12 | — | 180 | ||
12 | 20 | — | 60 | 6488 | 1464 | — | 130 | 534 | 602 | — | 140 | — | 13 | — | 120 | ||
13 | 20 | — | 30 | — | 186 | 875 | 40 | — | 346 | — | 20 | — | 16 | 727 | 60 | ||
14 | 10 | — | 110 | — | — | — | 260 | — | — | — | 170 | — | 16* | — | 340 | ||
15 | 20 | — | 60 | — | — | — | 90 | — | — | — | 80 | — | 17 | — | 250 | ||
16 | 50 | — | 190 | — | ND | ND | 130 | — | ND | ND | ND | ND | 9 | — | 130 | ||
17 | 30 | — | 70 | — | — | — | 150 | — | — | — | 170 | — | 16 | — | 110 | ||
18 | 10 | — | 230 | — | — | — | 60 | — | — | — | 170 | — | 18 | — | 250 | ||
19 | 10 | — | 80 | — | — | ND | 100 | — | — | — | 130 | — | 13 | — | 190 | ||
20 | 30 | — | 140 | — | — | ND | ND | ND | ND | ND | ND | 8 | — | 140 | |||
21 | 30 | — | 50 | — | — | — | 80 | — | — | — | ND | — | 14 | — | 130 | ||
22* | 30 | — | 120 | — | — | — | 190 | — | 148 | — | 400 | — | 22 | — | 500 |
CD4+ = CD4+ cell count (cells ×106/l); HAART = highly active antiretroviral therapy; PCR = quantitative polymerase chain reaction, in copies CMV ×106/ml; − = negative result; ND = not done; exam 0 = first examination, at intake, before the start of HAART; exam 1–7 = examinations, monthly, after the start of HAART. After the 7th examination, follow up scheduled every other month, results not shown. *Patient 9, 10, and 22 previous diagnosis of extraocular CMV disease.;†patient 7 one positive test 12 months after start HAART (280 copies/ml);
patient 14 one positive test 14 months after start HAART (98 copies/ml); last exam after n months = last examination of the patient at n months after the start of HAART.