Relation between stage of corneal dystrophy in patients with a βig-h3 R124H mutation and degree of corneal guttata
| Corneal dystrophy (βig-h3 R124H mutation) | Corneal guttata | |||
|---|---|---|---|---|
| None | Presence | Mild | Severe | |
| Stage 0 (normal; n=50) | 49 | 1 | 1/1 | 0/1 |
| Stage (I + II) (n=30) | 9 | 21 | 14/21 | 7/21 |
| Stage I(n=12) | 7 | 5 | 5/5 | 0/5 |
| Stage II(n=18) | 2 | 16 | 9/16 | 7/16 |
↵H=52.7, p<0.0001, Kruskul–Wallis ANOVA on ranks. Statistical analysis demonstrated that there was a significant relation between degree of corneal guttata and stage of the corneal dystrophy between degree of corneal guttata and stage of the corneal dystrophy.
↵p<0.05, Dann's test. The degree of corneal guttata has a tendency to increase as the stage of the corneal dystrophy with R124H mutation of βig-h3 gene increases.