Details of clinical data
| Case | Age | Sex | Main diagnosis | Associated disease | Previous Rx of ED | ED Size (mm) | Epithelialisation (weeks) | Surgery | F/U (M) | Result | Remarks |
| Group A | |||||||||||
| 1 | 80 | F | Neurotrophic | PBK | SCL, tear | 3 | 3 | AM | 24 | S | |
| 2 | 48 | M | Neurotrophic | Graft failure post PKP | SCL, tear | 3 | 1 | AM | 6 | S | |
| 3 | 69 | F | Neurotrophic | PBK, HSK, KCS, DM | SCL, tear, PO | 6 | 8 | AM | 7 | S | PKP at 7th month |
| 2nd AM, new site at 4th month | 4 | 1 | AM and patch tarsorrhaphy | S | |||||||
| 4 | 5 | M | Neurotrophic, LD | SJS | Tear, patch | 3 | 6 | AM | 30 | S | LT at 24th month |
| 5 | 70 | M | Neurotrophic | BK, KCS, DM | Tear, PO | 2 | 8 | AM | 19 | S | |
| 6 | 58 | F | Neurotrophic | BK, post bacterial ulcer | Patch | 2 | 1 | AM | 6 | S | |
| 7 | 9 | M | Exposure | Lid abnormality after tumour removal, post radiation, KCS | Tear, patch, tarsorrhaphy | 4 | 2 | AMs tarsorrhaphy | 18 | S | Tarsorrhaphy separation at 20th week |
| 2nd AM, new site at 6th month | 3 | 3 | AMs tarsorrhaphy | S | |||||||
| 3rd AM, new site at 7th month | 3 | 3 | AM | S | |||||||
| 8 | 68 | M | Neurotrophic, LD | PKP, trabeculectomy 5 times, KCS, DM | SCL, tear | 7 | 4 (not healed) | AM and patch | 3 | F | LT+PKP at 3rd month, ED healed in 8 days |
| 2nd AM, same site at 1st month | 3 | 8 (not healed) | AMs tarsorrhaphy | F | |||||||
| 9 | 40 | M | Neurotrophic, LD | Acute burn, lid abnormality | Tear, tarsorrhaphy | 5 | 3 | AMs tarsorrhaphy | 5 | S | |
| 10 | 55 | M | Neurotrophic | Fungal ulcer | Patch | 5 | 2 (not healed) | AM | 10 | F | |
| 2nd AM, same site at 0.5th month | 5 | 2 (not healed) | AM | F | Healed with antifungus | ||||||
| Group B | |||||||||||
| 1 | 33 | M | Neurotrophic | Post bacterial ulcer, post trauma | Tear | 4 | 1 | AM 2 layers | 14 | S | |
| 2 | 85 | F | Neurotrophic | HSK, KCS, DM | PO, SCL, tear | 3 | 3 | AM | 15 | S | |
| 3 | 58 | M | Neurotrophic | Post bacterial ulcer, BK | Tear | 3 | 4 | AM 2 layers | 5 | S | |
| 4 | 64 | F | Neurotrophic (descemetocele) | KCS, post radiation, uveitis, cataract | PO, tear | 3 | 1 | AM 2 layers | 6 | S | Enucleation due to painful eye at 6th month |
| 2nd AM, new site at 0.5th month | 3 | 1 | AM 2 layers | S | |||||||
| 3rd AM, new site at 1st month | 2 | 1 | AM 3 layers | S | |||||||
| 4th AM, new site at 1st month | 2 | 1 | AM 2 layers | S | |||||||
| 5th op, new site at 1st month | 2 | 1 | AM 2 layers | S | |||||||
| 5 | 61 | F | Neurotrophic (descemetocele) | Post trauma, post phacoemulsification | Tear, patch | 3 | 3 | AM 2 layers | 13 | S | |
| 6 | 50 | F | Neurotrophic | Post trauma, BK, DM | Tear | 3 | – | AM 3 layers | 13 | F | Lost AMT in 1 week |
| 2nd AM, same site at 1st month | 3 | 1 | AM 2 layers | S | |||||||
| 7 | 86 | F | Neurotrophic | KCS, HSK, post remove band keratopathy | SCL, patch | 3 | 3 (not healed) | AM 2 layers and patch | 15 | F | Healed with topical aciclovir in 1 week |
| 8 | 47 | F | Neurotrophic, exposure K (descemetocele) | Post radiation, lid abnormal post tumor removal | 4 | 1 | AM 2 layers | 15 | S | Exenteration at 15th month | |
| 9 | 41 | M | Neurotrophic, exposure K (descemetocele) | Lid abnormal post radiation, CA nasopharynx, KCS, S/P trabeculectomy | Tear | 3 | 1 | AM 2 layers + tarsorrhaphy | 10 | S | |
| 2nd AM, new site at 1.5th month | – | 3 | AM 3 layers | S | |||||||
| 10 | 56 | M | LD (descemetocele) | SJS, KCS | Tear, PO | 4 | 1 | AM 2 layers and patch | 5 | S | |
| 11 | 52 | F | Neurotrophic (descemetocele) | PBK | CL | 4 | 2 | AM | 9 | S | |
| 12 | 30 | F | Mooren's ulcer (descemetocele) | Glue, CL | 10 | 1 | AM 3 layers + remove glue | 6 | S | ||
| 13 | 73 | F | Neurotrophic, exposure (descemetocele) | KCS, ABK, post cataract extraction and pterygium excision | CL, tear | 4 | 2 (not healed) | AM 3 layers | 11 | F | AM loss at 2nd week |
| 2nd AM, same site at 0.5th month | 4 | 4 (not healed) | AM 3 layers | F | Healed with patch in 1 week | ||||||
| Group C | |||||||||||
| 1 | 38 | M | Neurotrophic, LD | SJS, KCS, S/P LT, PKP graft rejection | PO, tear, tarsorrhaphy | 3 | 0.5 | AM 3 layers | 1 | S | PKP at 1st month for vision |
| 2 | 34 | M | LD | SJS, KCS | PO | 3 | 1 | AM 3 layes | 20 | S | |
| 3 | 7 | F | Neurotrophic | HSK, post bacterial ulcer | – | 6 | 2 | AM 3 layers + glue | 5 | S | Remove glue at 1.5th month |
| 2nd op, 1.5th month (after glue removal) | 6 | 1 | AM 3 layers | S | PKP at 5th month for vision | ||||||
| 4 | 13 | M | Neurotrophic | Post bacterial ulcer, leukoma | – | 3 | 1 | AM 3 layers | 2.5 | F | Aqueous leak twice, AM slip, PKP at 2.5th month |
| 2nd AM, same site at 1st month | 3 | 1 | AM 3 layers | F | |||||||
| 5 | 34 | M | Neurotrophic | HSK | – | 6 | 1 | AM 6 layers | 11 | S | |
ED = epithelial defect, Rx = treatment, PBK = pseudophakic bullous keratopathy, SCL = soft contact lens, AM= amniotic membrane, PKP = penetrating keratoplasty, HSK = herpes simplex keratitis, KCS = keratoconjunctivitis sicca, DM = diabetic mellitus, PO = punctal occlusion, SJS = Stevens-Johnson syndrome, BK = bullous keratopathy, LD = limbal stem cell deficiency, ABK = aphakic bullous keratopathy, LT = limbal transplantation.