Table 1

Subretinal fluid ciprofloxacin levels following different application modes (μg/ml)

Patient no Topical ciprofloxacin Patient no Oral ciprofloxacin Patient no Topical+oral ciprofloxacin
10.2010.5211.92
20.3120.9420.93
30.2130.4830.54
40.0740.4140.58
50.5451.2151.41
60.2260.7460.81
70.1270.6672.12
80.4480.3681.28
90.1091.0190.50
100.15101.10100.63
110.24110.68110.86
120.11
Mean (SEM)0.23 (0.04)Mean (SEM)0.74 (0.09)Mean (SEM)1.05 (0.17)
  • Two drops of 0.3% solution every 30 minutes for 3 hours and every 60 minutes for the next 3 hours before the operation.

  • A single dose 1000 mg 6 hours before the operation.

  • A single dose 1000 mg 6 hours before the operation and two drops of 0.3% solution every 30 minutes for 3 hours and every 60 minutes for the next 3 hours before the operation.