Table 2

Results of heritability analysis for ocular refraction and its determiners based on aetiological model fitting. Parameter estimate (95% confidence interval of estimate)

Best fitting model A: Additive genetic effects D: Dominant genetic effects E: Unique environmental effects N
RefractionRight AE0.91 (0.86; 0.94)0.09 (0.06; 0.14)53/59
Refraction Left AE0.91 (0.86; 0.94)0.09 (0.06; 0.14)49/61
Refraction -transRight AE0.89 (0.82; 0.93)0.11 (0.07; 0.18)53/59
Refraction -trans Left AE0.91 (0.85; 0.94)0.09 (0.06; 0.15)49/61
Total refractionRight AE0.94 (0.90; 0.96)0.06 (0.04; 0.10)51/59
Total refraction Left AE0.93 (0.89; 0.96)0.07 (0.05; 0.11)49/60
Axial lengthRight AE0.94 (0.91; 0.96)0.06 (0.04; 0.09)53/59
Axial length Left AE0.94 (0.90; 0.96)0.06 (0.04; 0.10)49/60
ACDRight DE0.94 (0.90; 0.96)0.06 (0.04; 0.10)53/59
ACD Left DE0.88 (0.81; 0.92)0.12 (0.08; 0.19)50/61
Lens thicknessRight DE0.93 (0.89; 0.96)0.07 (0.05; 0.11)53/59
Lens thicknessLeft DE0.90 (0.85; 0.94)0.10 (0.06; 0.16)49/61
RadccRight AE0.90 (0.84; 0.93)0.10 (0.07; 0.16)52/59
RadccLeft AE0.92 (0.87; 0.95)0.08 (0.05; 0.13)49/61
  • Refraction -trans = refraction transformed to Gaussian distribution, ACD = anterior chamber depth and Radcc = mean radius of corneal curvature.

  • Estimated parameters:

  • A = proportion of phenotypic variation because of additive genetic effects.

  • D = proportion of phenotypic variation because of dominant genetic effects.

  • E = proportion of phenotypic variation because of unique environmental effects.

  • N = number of MZ/DZ pairs.