Reasons for withdrawal
| Reason | Drug | ||
|---|---|---|---|
| Timolol | Betaxolol | Carteolol | |
| Ocular | Eyes | Eyes | Eyes |
| No change or increase in IOP despite treatment | 5 | 14 | 5 |
| Initial fall IOP Rise to original level | 2 | 5 | 1 |
| Failure to achieve target IOP of < 21 mm Hg | 16 | 17 | 12 |
| Uncontrolled IOP (total eyes) | 23 | 36 | 18 |
| Average initial IOP | 27.74 (0.48) | 27.98 (0.43) | 27.78 (0.46) |
| Average initial IOP of those withdrawn | 30.4 (0.52) | 30.70 (0.54) | 30.75 (0.54) |
| Average IOP at withdrawal | 27.1 (0.40) | 28.5 (0.43) | 26.78 (0.41) |
| Other ocular | Eyes | Eyes | Eyes |
| Visual field deterioration with satisfactory reduction in IOP | 0 | 5 | 6 |
| Visual disturbance | 7 | 0 | 0 |
| Medical | Patients | Patients | Patients |
| Bradycardia | 1 | 2 | 1 |
| Breathlessness | 2 | 3 | 5 |
| Non-medical | |||
| Patient request for surgery (patients) | 1 | 0 | 2 |
| Moved away (patients) | 3 | 4 | 3 |
| Deceased (patients) | 3 | 4 | 6 |
| Other non-medical (patients) | 2 | 4 | 2 |