Description of discomfort upon instillation
| Day | Standard | Alginate | p Value (χ2) |
| 15 | 19 (16.5%) | 14 (11.7%) | 0.284 |
| Stinging | 15 | 6 | |
| Blurred vision | 0 | 2 | |
| Burning | 1 | 2 | |
| Miscellaneous | 3 | 4 | |
| 60 | 12 (10.7%) | 13 (11.1%) | 0.923 |
| Stinging | 10 | 10 | |
| Blurred vision | 2 | 1 | |
| Burning | 0 | 0 | |
| Miscellaneous | 0 | 2 | |
| 120 | 11 (9.9%) | 11 (9.6%) | 0.930 |
| Stinging | 6 | 5 | |
| Blurred vision | 0 | 2 | |
| Burning | 2 | 0 | |
| Miscellaneous | 3 | 4 |
Miscellaneous reports included: bad taste, discomfort, dry eye, flow in throat, grittiness, irritation, visual problem, and watering.