Intraocular pressure (mm Hg), mean blood pressure (mm Hg), and pulse rate (beats/min) (mean (SD))
| Measurement | Baseline | After treatment | Change from baseline (%) | p Value |
|---|---|---|---|---|
| Intraocular pressure | ||||
| Latanoprost | 15.5 (2.0) | 11.8 (1.7) | −3.7 (1.6) (−23.9%) | <0.001 |
| Brimonidine | 15.5 (2.0) | 12.9 (1.8) | −2.5 (1.2) (−16.1%) | <0.001 |
| ANOVA adjusted difference between the two regimens | 0.007 | |||
| Mean blood pressure | ||||
| Latanoprost | 91.6 (5.9) | 91.2 (8.3) | −0.4 (5.3) (−0.4%) | 0.703 |
| Brimonidine | 91.6 (5.9) | 88.2 (8.2) | −3.4 (7.2) (−3.7%) | 0.026 |
| ANOVA adjusted difference between the two regimens | 0.098 | |||
| Pulse rate | ||||
| Latanoprost | 67.9 (9.4) | 67.6 (10.0) | −0.3 (4.5) (−0.4%) | 0.739 |
| Brimonidine | 67.9 (9.4) | 65.8 (10.4) | −2.1 (4.2) (−3.1%) | 0.021 |
| ANOVA adjusted difference between the two regimens | 0.164 | |||