Clinical features
| Case | Sex | Age at presentation | Clinical features | B/L or U/L | Systemic features | Clinical diagnosis |
|---|---|---|---|---|---|---|
| HCD = horizontal corneal diameter, RE = right eye, LE = left eye, ASD = atrial septal defect, VSD = ventricular septal defect, U/L = unilateral, B/L = bilateral. | ||||||
| 1 (KL) | F | 3 days | Diffuse panstromal corneal clouding (see Fig 1) | B/L | Nil | Congenital glaucoma |
| 2 (CC) | M | 5 days | RE complete opaque cornea (see Fig 5) | U/L | CHARGE syndrome | Sclerocornea |
| Bilateral choanal atresia ASD, VSD, coarctation of aorta, micropenis | ||||||
| 3 (CC) | 20 days | RE opaque enlarged cornea with stromal vascularisation | U/L | Nil | Peters' anomaly | |
| ? Keratolenticular adhesion | ||||||
| 4 (KP) | F | 4 days | B/L dense central corneal opacities with peripheral irido-corneal adhesions | B/L | Orofacial digital syndrome | Peters' anomaly |
| Cleft lip and palate, brachycephaly, short femurs, brachydactyly, clinodactyly | ||||||
| 5 (MG) | M | 4 days | B/L corneal opacification with a central area of relative ectasia posterior embryotoxon (see Fig 3) | B/L | Nil | Corneal ectasia |
| 6 (SH) | F | 7 days | LE central corneal opacity with irido-corneal touch | U/L | Nil | Peters' anomaly |
| 7 (VCN) | M | 7 days | B/L scleralised corneas temporally | B/L | Nil | Sclerocornea |
| 8 (EF) | M | 5 days | Opaque corneas HCD 11 mm R and 11.5 mm L | B/L | Nil | Congenital glaucoma |
| 9 (NS) | M | 7.5 months | B/L opaque corneas with evidence of scleralisation | B/L | Nil | Sclerocornea |
| 10 (ET) | M | 6 weeks | B/L diffuse opaque corneas with complete scleralisation RE and some sparing inferiorly LE | B/L | Nil | Sclerocornea |
| 11 (TH) | M | 5 months | B/L diffuse opaque corneas with microcornea and scleralisation | B/L | Intrauterine growth retardation, failure to thrive | Sclerocornea |
| 12 (RM) | M | 7 days | B/L corneal ring opacities with thinning centrally | B/L | Peters' plus syndrome | Peters' anomaly |
| B/L cleft lip and palate, rhizomelia, clinodactyly, long philtrum | ||||||
| 13 (MR) | F | 7 days | RE central corneal opacity | U/L | Nil | Peters' anomaly |
| LE Axenfeld anomaly but clear cornea (see Fig 4) | ||||||