Table 1

Summary of the cases and the results

					Presence/absence of nuclear Smads3/4 positive cells
					Epithelial-type cells adjacent to regenerated lens fibres in Sommerring’s ring		Cells amid fibrous matrix accumulation
Case No	Age*	Sex	Duration	Cause†	Smad3	Smad4	Smad3	Smad4
*Age at the removal of the intraocular lens (IOL); † duration between implantation and explantation of the IOL; y = year(s); ‡CCC = continuous circular capsulorhexis; PVR = IOL removal to obtain the better observation of the fundus during vitrectomy for proliferative vitreoretinopathy; capsulotomy = obtained by anterior capsulotomy during cataract surgery; − = negative; + = positive (regardless the incidence of positive cells); NE = not examined.
1	65	F	−	CCC‡	−	−	−	−
2	72	M	−	CCC	−	−	−	−
3	58	M	−	CCC	−	−	−	−
4	72	F	−	Lens dislocation	−	−	−	−
5	28	M	6 days	IOL dislocation	+	+	NE	NE
6	64	M	10 days	PVR	+	+	NE	NE
7	58	F	14 days	PVR	+	+	NE	NE
8	68	F	0.65 y	PVR	+	+	+	+
9	75	F	0.75 y	PVR	+	+	+	+
10	51	M	1 y	Malignant glaucoma	+	+	+	+
11	53	M	3 y	PVR	+	+	NE	NE
12	75	M	2.7 y	IOL dislocation	+	+	+	+
13	78	M	4 y	PVR	+	+	+	+
14	80	M	4 y	PVR	+	+	+	+
15	76	M	4.6 y	IOL dislocation	+	+	+	+
16	68	M	5 y	IOL dislocation	+	+	+	+
17	77	F	5.4 y	PVR	+	+	+	+
18	77	F	6.2 y	IOL dislocation	−	−	+	+
19	60	M	8 y	IOL dislocation	−	−	NE	NE
20	68	M	9 y	IOL dislocation	+	+	NE	NE
21	31	M	10 y	IOL dislocation	−	−	−	−