Age adjusted relative risk (RR) of coronary heart disease (CHD) death or myocardial infarction (MI), by the presence of retinal abnormalities, among hypertensive participants of the LRC-CPPT
| Definite CHD | |||||||
|---|---|---|---|---|---|---|---|
| Retinal abnormalities | N | % | Death or MI | MI only | Death or MI in men with stage 1 hypertension* | Definite or suspected CHD | Any coronary event |
| Figures are age adjusted RRs. Figures in parentheses denote 95% confidence intervals. | |||||||
| *Defined by systolic and diastolic blood pressure levels of 140–159 and 90–99 mm Hg, respectively. | |||||||
| Any retinopathy | 65 | 11.6 | 2.1 (1.1 to 4.1) | 2.0 (1.0 to 4.2) | 2.2 (1.0 to 4.5) | 1.8 (1.0 to 3.2) | 1.3 (0.8 to 2.0) |
| Any retinopathy, except widened light reflex | 51 | 9.1 | 2.1 (1.0 to 4.3) | 1.9 (0.8 to 4.2) | 2.2 (1.0 to 4.8) | 1.8 (1.0 to 3.5) | 1.3 (0.8 to 2.0) |
| Arteriolar narrowing | |||||||
| Generalised or focal | 38 | 6.8 | 3.1 (1.5 to 6.3) | 2.7 (1.2 to 6.2) | 3.1 (1.4 to 7.1) | 2.7 (1.4 to 5.2) | 1.6 (1.0 to 2.6) |
| Generalised | 32 | 5.7 | 2.6 (1.2 to 5.8) | 2.1 (0.8 to 5.4) | 2.5 (1.0 to 6.3) | 2.5 (1.2 to 5.0) | 1.6 (1.0 to 2.8) |
| Focal | 8 | 1.4 | 2.9 (0.7 to 12.1) | 3.4 (0.8 to 14.2) | 4.0 (1.0 to 16.8) | 2.1 (0.5 to 8.5) | 0.7 (0.2 to 3.0) |
| Arteriovenous nicking | 18 | 3.2 | 1.8 (0.6 to 5.7) | 1.4 (0.3 to 5.6) | 2.9 (0.9 to 9.2) | 1.7 (0.6 to 4.8) | 1.0 (0.4 to 2.2) |
| Widened light reflex | 20 | 3.6 | 1.7 (0.5 to 5.4) | 2.0 (0.6 to 6.4) | 1.7 (0.5 to 5.6) | 1.2 (0.4 to 3.8) | 1.1 (0.5 to 2.4) |