Percentage of patients (%) | |||
---|---|---|---|
Category | Timolol + unoprostone (n=50) | Timolol + brimonidine (n=48) | Timolol + dorzolamide (n=48) |
*Considered by the investigator to be related or possibly related to study medication. | |||
†Events that occurred in >4% of the patients in any treatment group during adjunctive therapy. | |||
Overall summary: | |||
One or more drug related adverse events | 22.0 | 22.9 | 29.2 |
Ocular event | 18.0 | 10.4 | 22.9 |
Non-ocular event | 4.0 | 14.6 | 16.7 |
Most common† drug related events: | |||
Abnormal vision | 0.0 | 4.2 | 0.0 |
Burning/stinging | 4.0 | 4.2 | 14.6 |
Burning/stinging upon drug instillation | 8.0 | 0.0 | 2.1 |
Dry mouth | 0.0 | 2.1 | 4.2 |
Foreign body sensation | 4.0 | 4.2 | 0.0 |
Headache | 0.0 | 4.2 | 2.1 |
Hypertension | 0.0 | 4.2 | 0.0 |
Itching | 0.0 | 8.3 | 0.0 |
Lacrimation disorder | 2.0 | 2.1 | 4.2 |
Nausea | 0.0 | 0.0 | 4.2 |
Tachycardia | 0.0 | 2.1 | 4.2 |
Taste perversion | 0.0 | 0.0 | 4.2 |
Vertigo | 0.0 | 2.1 | 6.3 |