Table 1

Lewis phenotypes

Name of phenotype	Le^a	Le^b	Le^c	Le^d
*Anti-Le^b MAbs faintly react with Le^a antigen.⁹
Lewis positive (Le (a+b−) and Le (a−b+)) patients can be detected by anti-Le^a, anti-Le^b, and/or anti-sialyl Le^a Mabs. Non-secretor patients include those with Le^a phenotype (detected by anti-Le^a Mabs) and Le^c phenotype which fails to immunoreact with any anti-Lewis and anti-H type 2 Mabs. Secretor patients are detected by anti-Le^b but also by anti-H type 2 Mabs.
Structures	βGal	αFuc1-2βGal	βGal	αFuc1-2βGal
	1	1	1	1
	3	3	3	3
	αFuc1-4βGlcNAc	αFuc1-4βGlcNAc	βGlcNAc	βGlcNAc
Secretor(FUT2)	–	+	–	+
Lewis (FUT3/5)	+	+	–	–
Red cell phenotype	Le(a+b−)	Le(a−b+)	Le(a−b−)	Le(a−b−)
Frequency in white people (%)	20	70	1	9
MAbs reactivity
Anti-Le^a	+++	–	–	–
Anti-Le^b	+*	+++	–	–
Anti–S Le^a	+++	+++	–	–
Anti-H-Type 2	–	+++	–	+++