Immunohistological staining using anti-blood group related antigen Mabs on the conjunctiva of the 22 OCP patients and the 89 normal individuals18
| Ph | No* | % | Intensity of staining | Intensity of staining | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Epithelial cells | Goblet cells | ||||||||||
| Lea | S-Lea | Leb | H-type 2 | Lea | S-Lea | Leb | H-type2 | ||||
| OCP, ocular cicatricial pemphigoid; N, normal conjunctiva; Ph, phenotype; Lea, anti-Lea (7LE); S-Lea, anti-sialyl-Lea (NS 19-9); Leb, anti-Leb (2–25 LE); positive reaction from + to +++ represent increasing number of stained cells and intensity staining; NA, not applicable; −, negative staining; *number of individuals; †goblet cells were found only in 5/7 Lea OCP patients; ‡goblet cells were found only in 11/13 Leb OCP patients. | |||||||||||
| N | Lea | 17 | 20 | +++ | +++ | + | – | +++ | +++ | + | – |
| OCP | Lea | 7 | 32 | +/++ | +/++ | +/− | – | +/−† | +/−† | +/− † | –† |
| N | Leb | 63 | 70 | – | +++ | +++ | +++ | +++ | +++ | + | + |
| OCP | Leb | 13 | 59 | – | +/− | +/++ | ++ | +/−‡ | +/−‡ | +/−‡ | +‡ |
| N | Lec | 0 | 0 | NA | NA | NA | NA | NA | NA | NA | NA |
| OCP | Lec | 2 | 9 | – | – | – | – | – | – | – | – |
| N | Led | 9 | 10 | – | – | – | ++ | – | – | – | ++ |
| OCP | Led | 0 | 0 | NA | NA | NA | NA | NA | NA | NA | NA |