Published reports of photodynamic therapy of circumscribed choroidal haemangioma*
| Author | Year | No of eyes | Primary or secondary | Median follow up (range) months | Method of treatment | Results eyes (%) | Complications (eyes) | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Protocol | Spots | Sessions | Tumour regression | Vision improved or stable | ||||||
| Standard: 10 minute infusion of 6 mg/m2 verteporfin, laser application 5 minute after completion of infusion and laser settings; power = 50 J/cm2, intensity = 600 mW/cm2, duration = 83 seconds. | ||||||||||
| *Excluding single case reports. | ||||||||||
| †Laser application 10 minute after completion of infusion. | ||||||||||
| Barbazetto12 | 2000 | 2 | 2/0 | 11 (9–12) | Standard 100 J/cm2 168 s | ⩾1 Overlapping | 2–4 | 2 (100%) | 2 (100%) | None |
| Madreperla13 | 2001 | 3 | 3/0 | 4 (3–9) | Standard | 1 | 1 | 3 (100%) | 3 (100%) | None |
| Robertson14 | 2002 | 3 | 3/0 | 13 (11–14) | Standard† | ⩾1 Overlapping | 1–2 | 3 (100%) | 3 (100%) | None |
| Schmidt-Erfurth15 | 2002 | 15 | 15/0 | 19 (12–50) | Bolus (1 min) 100 J/cm2 166 s | 1 | 1–4 | 15 (100%) | 15 (100%) | None |
| Landau16 | 2002 | 8 | 4/4 | 7 (3–15) | Standard | ⩾1 (?) | 1–2 | 7 (88%) | 7 (88%) | Choroidal effusion and perifoveal haemorrhage (1) |
| Jurklies17 | 2003 | 19 | 15/4 | 11 (2–24) | Bolus (2 min) 100 J/cm2 166 s | ⩾1 non-overlapping | 1–5 | 19 (100%) | 18 (95%) | None |
| Verbraak18 | 2003 | 13 | 11/2 | 12 (3–22) | Bolus (1 min) 50–100 J/cm2 83–166 s | 1 | 1–2 | 13 (100%) | 13 (100%) | None |
| Porrini19 | 2003 | 10 | 7/3 | 13 (7–16) | Standard 75–100 J/cm2 125–186 s/ | 1 | 1–3 | 10 (100%) | 10 (100%) | None |
| Present study | 2004 | 10 | 7/3 | 7 (1–13) | Standard | ⩾1 Overlapping | 1–2 | 10 (100%) | 8 (80%) | Choroidal atrophy (2) |