Clinicopathological characteristics of the study groups
| Characteristic | Group I (n = 114) | Group II (n = 31) | p Value |
|---|---|---|---|
| *Defined as involvement of the medial quarter of the upper or lower lid and/or the angle. | |||
| †Defined as involvement of the lateral quarter of the upper or lower lid and/or the angle. | |||
| ‡Refers to maximal tumour diameter. | |||
| §Infiltrative growth component was defined as a portion or all of the tumour consisting of elongated strands of infiltrating BCC tumour cells. | |||
| ¶Positive margins were defined as the presence of tumour cells at one or more cut surfaces of the surgical specimen. | |||
| N, number; N/A, not applicable; PPS, postoperative paraffin section. | |||
| Mean age (range) (years) | 71.5 (44–94) | 65.9 (45–91) | N/A |
| Female:male ratio | 1.0:0.9 | 1.0:1.3 | N/A |
| Anatomical location, n (%) | |||
| Medial canthal region* | 55 (48.2) | 11 (35.5) | p<0.05 |
| Lower lid, central | 33 (28.9) | 10 (32.2) | p>0.05 |
| Lateral canthal region† | 20 (17.5) | 7 (22.6) | p>0.05 |
| Lower lid, entire lid | 5 (4.5) | 3 (9.7) | p>0.05 |
| Upper lid, central | 1 (0.9) | 0 (0.0) | p>0.05 |
| Mean tumour size (range) (mm)‡ | 13.3 (2–32) | 12.9 (5–18) | N/A |
| Histopathology§ | |||
| Infiltrative growth pattern, n (%) | 24 (21.0) | 7 (22.6) | p>0.05 |
| Circumscribed growth pattern, n (%) | 90 (79.0) | 24 (77.4) | p>0.05 |
| Histopathological margins¶ | |||
| Positive margins on PPS, n (%) | 0 (0.0) | 3 (9.7) | p = 0.002 |
| Follow up and recurrence rate | p = 0.002 | ||
| Mean follow up period (range) (years) | 6.4 (5.0–11.1) | 6.9 (5.0–14.1) | |
| Recurrences after resection, n (%) | 0 (0.0) | 3 (9.7) | |
| Mean time to recurrence (range) (years) | N/A | 5.1 (1.9–10.6) | |