Table 2

Five year incidence of age related maculopathy (ARM) lesions by presence of focal arteriolar narrowing at baseline

ARM lesionFocal arteriolar narrowingNo at riskNo affected (%)Age adjusted relative risk* (95% CI)Age/sex adjusted odds ratio† (95% CI)Age/sex/smoking/mean arterial BP adjusted odds ratio† (95% CI)
*Mantel-Haenszel estimates.
†Logistic regression estimates.
Late stage ARM
Neovascular AMDabsent215218 (0.8)1.01.01.0
present1625 (3.1)2.1 (0.8 to 5.8)1.8 (0.6 to 5.2)2.0 (0.7 to 6.0)
Geographic atrophyabsent215213 (0.6)1.01.01.0
present1624 (2.5)2.2 (0.7 to 7.0)1.9 (0.6 to 6.3)1.8 (0.5 to 6.1)
Either late stage ARM lesionabsent215226 (1.2)1.01.01.0
present1628 (4.9) 2.3 (1.0 to 5.1) 2.0 (0.9 to 4.7)2.1 (0.9 to 4.9)
Early stage ARM lesions
Pigment abnormalityabsent1880161(8.6)1.01.01.0
present12516 (12.8)1.2 (0.7 to 1.9)1.1 (0.6 to 1.9)1.1 (0.6 to 2.0)
Indistinct soft/reticular drusenabsent2011102 (5.1)1.01.01.0
present13712 (8.8)1.1 (0.7 to 2.0)1.0 (0.5 to 2.0)1.0 (0.5 to 1.9)
Early stage ARMabsent2061174 (8.4)1.01.01.0
present14223 (16.2)1.4 (0.9 to 2.0)1.3 (0.8 to 2.2)1.3 (0.8 to 2.1)