Table 4

Change in IOP during the study

OverallBrimonidine (n = 31)Timolol (n = 28)p Value
Presenting IOP
    Mean (SD)57.5 (12.1)55.2 (12.3)60.0 (11.5)
    Range30–8030–7430–800.13
    Median60.058.061.0
IOP after LPI
    Mean (SD)12.4 (4.1)12.6 (4.7)12.3 (3.3)
    Range4–224–225.7–18.70.76
    Median12.012.012.0
IOP after visual field at week 1
    Mean (SD)14.3 (4.5)14.4 (4.8)14.2 (4.3)
    Range5.3–28.76.7–28.75.3–24.70.89
    Median14.013.714.0
IOP at week 4
    Mean (SD)16.9 (6.5)17.6 (7.2)16.2 (5.6)
    Range6.7–36.76.7–36.78–320.39
    Median15.316.015.0
IOP at week 8
    Mean (SD)16.9 (4.1)17.8 (4.2)16.0 (3.9)
    Range9.7–27.310–27.39.7–25.70.09
    Median16.718.315.8
IOP at week 12
    Mean (SD)16.9 (4.7)17.0 (4.5)16.8 (5.1)
    Range7.3–30.37.3–30.37.7–26.00.88
    Median16.716.716.8
IOP at week 16
    Mean (SD)16.5 (3.7)16.5 (3.0)16.5 (4.4)
    Range9.3–29.710–249.3–29.70.94
    Median16.017.016.0