Table 1

Clinical data of blood pressure, heart rate, intraocular pressure, and calculated ocular perfusion pressure at baseline and after 2 weeks of treatment (mean (SD))

BrinzolamidePlacebo
BaselineDrugBaselinePlacebo
Apart from a significant decrease of intraocular pressure after brinzolamide no significant differences between visits were detected in both groups (ANOVA for repeated measures).
*p<0.0001 (Bonferroni-Dunn).
Systolic blood pressure (mm Hg)120 (17)118 (13)117 (9)120 (12)
Diastolic blood pressure (mm Hg)73 (11)71 (8)70 (7)72 (9)
Heart rate (beats/min)66 (9)69 (9)67 (11)66 (14)
Intraocular pressure (mm Hg)12.3 (2.0)9.4 (2.2)*13.2 (1.6)12.3 (2.2)
Ocular perfusion pressure (mm Hg)46.2 (8.2)47.8 (5.4)43.2 (5.0)45.7 (6.0)