Thickness variations of extraocular muscles relative to optic nerve size—efficacy population
| Muscles | Treatment group* (n = 46) | Non-treatment group (n = 28) | Difference between groups |
|---|---|---|---|
| n, number of eyes; *n = 45 for lateral rectus; †not significant. | |||
| Inferior rectus: | |||
| Week 0 | p = 0.0184 | ||
| Mean (SD) | 1.3 (0.7) | 0.9 (0.3) | |
| Range | (0.4–3.2) | (0.3–2.0) | |
| Week 24, percentage change | p = 0.1173† | ||
| Mean (SD) | −13.2 (25.7) | −4.0 (21.5) | |
| Range | (−60.6–69.1) | (−63.6–42.6) | |
| Medial rectus: | |||
| Week 0 | p = 0.0153 | ||
| Mean (SD) | 1.2 (0.6) | 0.9 (0.3) | |
| Range | (0.5–3.1) | (0.5–1.5) | |
| Week 24, percentage change | p = 0.0900† | ||
| Mean (SD) | −8.2 (20.7) | 0.6 (22.4) | |
| Range | (−42.8–42.8) | (−27.8–66.7) | |
| SRLP: | |||
| Week 0 | p = 0.0506† | ||
| Mean (SD) | 1.2 (0.6) | 0.9 (0.3) | |
| Range | (0.5–3.2) | (0.5–1.8) | |
| Week 24, percentage change | p = 0.0060 | ||
| Mean (SD) | −9.5 (29.1) | 12.5 (37.5) | |
| Range | (−63.8–78.6) | (−41.7–139.2) | |
| Lateral rectus: | |||
| Week 0 | p = 0.0662† | ||
| Mean (SD) | 1.0 (0.4) | 0.9 (0.4) | |
| Range | (0.4–2.1) | (0.4–1.8) | |
| Week 24, percentage change | p = 0.0765† | ||
| Mean (SD) | −11.5 (20.6) | −0.5 (31.6) | |
| Range | (−63.1–39.2) | (−51.6–87.5) | |