Table 3

 The results of analysis of covariance to investigate the statistical significance of the trial primary outcome measures

Model 1Model 2
Coefficientp ValueCoefficientp Value
Model 1: adjusted for baseline differences in acuity and central macular thickness only.
Model 2: adjusted for baseline differences in acuity, central macular thickness, insulin use, duration of diabetes, and glycosylated haemoglobin. Model 2 for ETDRS logMAR visual acuity was additionally adjusted for cataract progression.
ETDRS logMAR VA0.0990.2770.2650.123
OCT central macular thickness−20.1780.746−7.2890.919