The influence of normal pressure glaucoma (NPG) on maximum relaxation (%) and sensitivity (−logIC50) of acetylcholine mediated relaxation in human resistance arteries
| Control | NPG | |||
|---|---|---|---|---|
| Emax | −logIC50 | Emax | −logIC50 | |
| Values are expressed as mean (SEM) for arteries from (n) patients. *p<0.05 compared with arteries from control subjects, using Student’s unpaired t test. †−logIC50 not measurable because of to small relaxation. | ||||
| Control | 95.5 (2.0) (7) | 7.34 (0.12) (7) | 93.4 (2.0) (7) | 7.70 (0.11) (7)* |
| L-NOARG/Indo | 74.3 (3.5) (5) | 6.91 (0.11) (5) | 72.0 (5.1) (6) | 6.84 (0.15) (6) |
| ODQ | 71.3 (7.6) (5) | 6.98 (0.27) (5) | 81.3 (2.6) (4) | 7.15 (0.22) (4) |
| ChTx/Apa | 81.8 (6.0) (5) | 6.85 (0.21) (5) | 55.4 (8.16)* (4) | 6.92 (0.06) (4) |
| NOARG /Indo/ChTx/Ap | 15.9 (5.0) (4) | −† | 0.7 (0.4) (4) | −† (4) |