Physiological variables
| Hours after LPS injection | |||||||
|---|---|---|---|---|---|---|---|
| Control | 6 hours | 12 hours | 24 hours | 48 hours | 72 hours | 96 hours | |
| Values are means (SEM). (n = 6 at each time point in both groups) | |||||||
| WBC, peripheral leucocyte count; MABP, mean arterial blood pressure. | |||||||
| Blood glucose level in diabetic rats was significantly higher than that in non-diabetic rats at each time point. There were no significant differences between non-diabetic and diabetic rats in other physiological parameters. *p<0.05 compared with control values in each group. †p<0.05 compared with values of non-diabetic rats at each time point. | |||||||
| Non-DM groups | |||||||
| WBC (×106/l) | 8.6 (0.8) | 7.8 (1.0) | 7.3 (0.9) | 7.7 (1.9) | 13.3 (1.4)* | 10.9 (1.1) | 9.4 (1.1) |
| Blood glucose (mg/ml) | 137 (4) | 132 (6) | 135 (4) | 133 (6) | 135 (6) | 133 (6) | 133 (6) |
| MABP (mm Hg) | 100 (5) | 101 (4) | 106 (5) | 103 (7) | 102 (4) | 101 (6) | 100 (6) |
| DM groups | |||||||
| WBC (×106/l) | 8.1 (0.3) | 6.7 (1.3) | 7.4 (0.8) | 7.7 (0.5) | 11.1 (0.5)* | 9.6 (0.9) | 8.7 (1.2) |
| Blood glucose (mg/ml) | 325 (24)† | 351 (16)† | 331 (16)† | 314 (59)† | 350 (34)† | 351 (16)† | 343 (6)† |
| MABP (mm Hg) | 98 (3) | 96 (4) | 97 (7) | 98 (7) | 100 (6) | 98 (6) | 99 (5) |