Human cadaveric | Whole eye cross sections | In vitro ligand binding and autoradiography | α2 | +++ iris and ciliary epithelium | 26 |
| | | | ++ciliary muscle, retina, RPE (and/or choroid) | |
Rats and rabbits | Whole eye cross sections | Autoradiography | α2 | Ciliary processes | 27, 28 |
| | | | Ocular muscles | |
| | | | Retina and RPE | |
Human | Cornea | Immunofluorescence | α2A, α2B, α2C | α2A, α2B and α2C: cornea | 29 |
| Ciliary body | | | α2B and α2C: ciliary body | |
Rabbit | Ciliary body | Immunofluorescence/polymerase chain reaction/dot blot hybridisation | α2A, α2B, α2C | α2A: positive in rabbit ciliary body by immunofluorescence | |
| | | | RNA encoding: α2A, α2B, α2C all present in rabbit iris-ciliary body | |
Human and bovine | Retinal homogenates | Radioligand binding | α-adrenergic | Retina | 30–33 |
Human | Trabecular meshwork cells | Immunofluorescence | α2A, α2B, α2C | α2A | 34 |
Human | Ciliary body | Radioligand binding | α2A, α2B, α2C | α2A: | 35 |
| RPE-CC | | | +++ iris | |
| Iris | | | ++ RPE-CC and ciliary body | |
| Retina | | | + retina | |
Bovine | Retina | Radioligand binding | α2A, α2B, α2C, α2D | α2D +++ | 23, 36 |
| | | | α2A + | |
Porcine | Iris | Radioligand binding | α2A, α2B, α2C | α2A in iris, ciliary body, and choroid | 24 |
| Ciliary body | | | α2A and α2C in retina | |
| Choroid | | | | |
| Retina | | | | |
Rabbit | Iris-ciliary body membranes | Radioligand binding | α1 and α2 adrenergic | α2 subtype in iris-ciliary body membrane | 37 |
Rabbit | Ciliary body | Radioligand binding | α1 and α2 adrenergic | α2 subtype in ciliary body | 38 |
Rat | Retina | Radioligand binding | α1 and α2 adrenergic | α1 subtype in OPL | 39 |
| | | | α2 subtype ++ IPL, + INL and GCL | |
Rat | Retina | Immunohistochemistry | α2A | α2A in the GCL and INL | 3 |