Outcome measurements by time and treatment group*
| Characteristics | 3 months | 6 months | 12 months | |||
|---|---|---|---|---|---|---|
| “Classic” (n = 14) | “Light” (n = 15) | “Classic” (n = 14) | “Light” (n = 15) | “Classic” (n = 14) | “Light” (n = 15) | |
| *Data are given as number (%) of patients except where noted. | ||||||
| †Calculated with the Fisher’s exact test. | ||||||
| ‡Calculated with the t test. | ||||||
| §Calculated with the U-Mann Whitney test. | ||||||
| Change in FTH on OCT | Light (n = 14) | Light (n = 14) | Light (n = 14) | |||
| Decreased | 5 (36) | 4 (29) | 7 (50) | 6 (43) | 7 (50) | 6 (43) |
| Unchanged | 7 (50) | 8 (57) | 5 (43) | 3 (21) | 4 (29) | 3 (21) |
| Increased | 2 (14) | 2 (14) | 2 (14) | 5 (36) | 3 (21) | 5 (36) |
| p Value† | 1 | 0.50 | 0.79 | |||
| Mean (SD) change in FTH(μm) (post-treatment value minus pretreatment value) | −48.21 (88) | −15.86 (46) | −63.78 (105) | −14.86 (85) | −47.86 (121) | 6.36 (135) |
| p Value‡ | 0.232 | 0.189 | 0.274 | |||
| Change in CSMO on biomicroscopy | ||||||
| Reduced/eliminated | 8 (57) | 4 (26) | 7 (50) | 5 (33) | 10 (71) | 5 (33) |
| Increased | 0 (0) | 1 (7) | 0 (0) | 2 (13) | 2 (14) | 2 (13) |
| p Value† | 0.19 | 0.54 | 0.09 | |||
| Reduction/resolution of leakage on FA | 8 (57) | 9 (56) | 11 (79) | 10 (63) | 10 (71) | 9 (56) |
| p Value† | 0.96# | 0.68 | 0.70 | |||
| Change in visual acuity | ||||||
| ⩾5 letters increase | 4 (29) | 3 (20) | 2 (14) | 7 (47) | 5 (36) | 5 (33) |
| No change | 8 (57) | 12 (80) | 12 (86) | 6 (40) | 7 (50) | 8 (53) |
| ⩾5 letters decrease | 2 (14) | 0 (0) | 0 (0) | 2 (12) | 2 (14) | 2 (13) |
| p Value† | 0.29 | 0.03 | 1 | |||
| Mean (SD) change in No of letters (post-treatment value minus pre-treatment value) | 2.00 (5.22) | 0.80 (3.36) | 1.93 (4.56) | 2.27 (5.75) | 3.07 (6.50) | 0.80 (6.82) |
| p Value‡ | 0.46 | 0.86 | 0.37 | |||
| Mean (SD) change in mean deviation of central 10° sensitivity (post-treatment value minus pretreatment value) | −0.81 (1.61) | −0.66 (1.39) | −0.04 (1.39) | −0.03 (1.84) | ||
| p Value‡ | 0.82 | 0.99 | ||||
| Mean No (SD) of scotomata | 7.92 (6.76) | 7.28 (6.63) | 5.00 (4.96) | 4.78 (5.87) | ||
| p Value§ | 0.63 | 0.40 | ||||
| Change (SD) in contrast sensitivity (No of letters) | −0.36 (2.50) | −0.07 (1.62) | −0.71 (2.84) | −0.40 (2.67) | −1.21 (3.51) | −0.27 (2.76) |
| p Value§ | 0.75 | 0.85 | 0.56 | |||
| No of eyes retreated | 0 | 0 | 1 (7) | 3 (20) | 4 (29) | 3 (20) |
| p Value† | 0.60 | 0.68 | ||||