Table 2

 Human ocular expression of TLRs

Ocular tissueCell typeTLR*
APCs, antigen presenting cells; RPE cells, retinal pigment epithelial cells.
*mRNA expression only, unless otherwise specified.
†TLR protein expression confirmed.
CorneaCorneal epitheliumTLR1, 2†, 3, 4†, 5†, 6, 7, 9, 1013,14,17
Cultured corneal epithelial cellsTLR1, 2†, 3†, 4†, 5†, 6, 911–14,17
Cultured corneal fibroblastsTLR419
ConjunctivaWhole bulbar conjunctivaTLR428
UveaResident stromal APCsTLR4†28,31
Cultured iris endothelial cellsTLR431
RetinaWhole retinaTLR428
Cultured RPE cellsTLR1, 2†, 3†, 4†, 5, 6, 7, 9, 1035,40
ScleraWhole scleraTLR428