Table 1

Summary of clinical features of 21 patients with retinitis pigmentosa included in the study

Patient	Figure	Age	Nyctalopia (years)	Visual field loss	Bone-spicule pigment	Inheritance	Other symptoms/signs or genetic marker
MfERGs were performed on all patients apart from case 21. Serial AF images from cases 6, 7, and 21 are shown in figure 9A, B, and C, respectively. Inheritance is shown as dominant (D) or recessive (R) where known. NR, not reported. ND, not detected.
1	1A, 2A	47	+(10)	+	+
2	1B, 2B	51	+(20)	+	+	D
3	1C, 2C	22	NR	NR	ND	D	Mild peripheral pigmentary disturbance. Asymptomatic
4	5, 7C, 7D	38	+ (>20)	+	+		Photopsias, vitreous opacities
5	6, 7E, 7F	41	+	+			Ring scotoma
6	7G, 7H, 9A, 10	26	+(3)	+	+	R	Usher 2. Attenuated vessels, disc pallor, epiretinal membranes
7	9B	33	+ (2)	NR	ND	R	Usher 2. Attenuated vessels. Peripheral pigment and atrophy
8		28	+ (18)	+	ND	R	Intra-retinal pigment
9		31		+	+
10		23	+ (3)	+	+	D	Peripheral atrophy, pigment migration, epiretinal membranes
11		25	NR	NR	ND	D	RP18. Attenuated vessels, right amblyopia
12		16		+	+	R	Usher 2
13		46	+ (>25)	+	+		Pale discs, attenuated vessels
14		35	+(17)	+	+	D	Attenuated vessels
15		36	+(1)	+	+
16		31	NR	+	ND
17		36	+(>20)	+	+	D	Pale discs, amblyopia left eye
18		34	+(1–2)	+	+	D
19		33	+	+	+	D	Atrophic areas close to arcades
20		42	+	+	+	D
21	9C	11	+ (>5)	NR	ND		Attenuated vessels, pale fundi