Table 2 Mutations in the quinolone resistance determining regions of gyrA, parC and parE in 70 strains of Staphylococcus epidermidis
Mutation typeNo of isolatesMutation
gyrAgyrBparCparE
128Ser84PheSer80Tyr
21Ser84PheSer80Tyr + Asp84Val + Ala85Ser
34Ser84PheSer80Phe
44Ser84PheSer80Phe + Asp84Tyr
51Ser84PheSer80Phe + Asp84Asn
62Ser84PheAsp84Tyr
75Ser84TyrSer80Phe
83Ser84TyrSer80PheAsp434Asn
91Ser84Tyr + Glu88LysSer80Phe + Asp84Ala
102Ser84TyrSer80Tyr
111Ser84TyrSer80Ile
121Ser84IleSer80PheAsn404Ser + Asp434Asn
131Ser80TyrAsn404Ser
141Ser80Phe
151Asp69Asn
161Ser81Pro
171Asp84Gly
1811Asn404Ser
191Asp434Asn