Table 2 Analysis of extracellular conjunctival tissue changes: area occupied by collagen fibres, amorphous material and empty spaces in the subepithelial and deep layer in the control-, timolol- and latanoprost group
GroupCollagen fibresAmorphous materialEmpty spaces
Subepithelial layer
    Control40.3 (15.3)30.9 (12.8)28.8 (20.2)
    Timolol43.3 (17.4) (p>0.05)43.3 (13.2) (p<0.001)13.4 (9.5) (p<0.001)
    Latanoprost42.9 (13.2) (p>0.05)38.1 (10.1) (p<0.001)19.0 (10.5) (p<0.01)
Deep layer
    Control33.5 (14.6)26.6 (12.2)39.9 (20.9)
    Timolol36.6 (13.2) (p>0.05)35.1 (9.8) (p<0.001)32.8 (15.1) (p<0.05)
    Latanoprost31.8 (10.4) (p>0.05)31.1 (10.4) (p<0.001)32.7 (14.9) (p<0.05)

  • Data are presented as mean percentage (SD) (p values) relative to control group are indicated below.