Serious ocular adverse event | No of subjects | % Per injection |
Endophthalmitis | 2† | 0.05% |
Vitreous haemorrhage | 2 | 0.05% |
Conjunctival irritation | 1 | 0.02% |
Retinal haemorrhage | 1 | 0.02% |
Retinal tear | 1 | 0.02% |
Vitreous opacities | 1 | 0.02% |
Ocular adverse events reported in ≥5% of study eyes, N (%) | ||
Punctate keratitis | 73 (12.9) | |
Eye pain | 61 (10.7) | |
Vitreous floaters | 57 (10.0) | |
Conjunctival haemorrhage | 36 (6.3) | |
Eye irritation | 34 (6.0) | |
Visual acuity reduced | 31 (5.5) | |
Macular degeneration | 28 (4.9) |