All nervous system | 13 (2.3) |
Cerebrovascular accident | 3 (0.5) |
Cerebral infarction | 1 (0.2) |
All cardiac | 30 (5.3) |
Myocardial infarction | 4 (0.7) |
Acute coronary syndrome | 1 (0.2) |
Coronary artery occlusion | 1 (0.2) |
Myocardial ischaemia | 1 (0.2) |
All non-ocular haemorrhagic | 2 (0.4) |
Haematuria | 1 (0.2) |
Other non-ocular adverse events reported in over 2% of subjects |
Hypertension | 43 (7.6) |
Urinary tract infection | 26 (4.6) |
Sinusitis | 25 (4.4) |
Gastro-oesophageal reflux | 21 (3.7) |
Pneumonia | 20 (3.5) |
Benign prostatic hyperplasia | 10 (4.3)† |
Cardiac failure, congestive | 18 (3.2) |
Bronchitis | 19 (3.3) |
Nasopharyngitis | 16 (2.8) |
Headache | 16 (2.8) |
Nausea | 15 (2.6) |