Table 4

Literature review of outcomes of treatment of CMV anterior uveitis in non–HIV-positive patients

AuthorsNo. eyes treatedTreatment modality and duration in monthsOutcomeDuration of follow-up (months)
Chee et al212Intravenous ganciclovir at 5 mg/kg of body weight twice a day for 6 weeks, followed by oral ganciclovir at 1 g three times a day for another 6 weeks or oral valganciclovir at 900 mg twice a day for 6 weeks, followed by 450 mg twice a day for another 6 weeks, 9 cases; 12 weeks of intravitreal ganciclovir at 2 mg/week, 3 cases1 responded with no recurrence, 6 responded but had recurrences, 2 had no response, 2 responded with no recurrence and 1 had recurrences14–43
Mietz et al51Intravenous ganciclovir at 450 mg twice daily×4 weeks and oral 3 g/day×19 weeksResponded but recurredUnknown
Markomichelakis et al62Oral ganciclovir at 3 g/day×52 weeks, 1 case; oral ganciclovir at 3 g/day×104 weeks, 1 caseBoth responded with no recurrencesUnknown
De Schryver et al75Intravenous ganciclovir or foscarnet×2 weeks followed by oral valganciclovir 450 mg twice daily×8 weeks, 4 cases; 12 weeks oral valganciclovir, 1 case3 responded but recurred; retreated with oral valganciclovir for 6 months, responded with no recurrence9–24
Van Boxtel et al85Oral valganciclovir at 900 mg twice daily×3 weeks followed by 900 mg/day for 3–12 monthsAll responded; two had recurrences18–249
Chung and Chua1011 dose intravitreal ganciclovirResponded with no recurrenceUnknown
Sira and Murray12111 months oral valaciclovir at 1 g twice a dayResponded with no recurrence11
Hwang et al1861 dose of intravitreal 2 mg ganciclovir followed by oral valganciclovir at 900 mg twice a day×1–4 months, 4 cases; 1 dose of intravitreal ganciclovir at 2 mg, 2 casesResponded with no recurrence12–22