RPE-choroid sheet TX (group 1) | RPE cell-suspension TX (group 2) | p Value | |
Patients (n) | 7 | 7 | |
Mean age (range, years) | 77 (72–82) | 79 (71–84) | 0.35 |
Sex | 5 women, 2 men | 4 women, 3 men | 1.0 |
Mean lesion size (range, mm) | 7.8 (3.5–10) | 6.1 (4.9–9.2) | 1.0 |
Diagnosis (n) | 0.59 | ||
Classic CNV with haemorrhage | 5 | 3 | |
Occult CNV, occult and classic CNV | 2 | 4 | |
Non-responder to previous therapy (n) | 5 | 2 | 0.29 |
Distance BCVA (mean±SD, ETDRS chart) | 0.25±0.22 | 0.28±0.23 | 0.75 |
Range | LP (n=2) to 0.55 | 0.04–0.53 | |
Near BCVA (mean±SD, logRAD) | 1.3±0.7 | 1.3±0.7 | 0.79 |
Range | NRA (n=2) to 0.6 | NRA (n=2) to 0.4 | |
Mean RT (range, μm) | 565 (398–750) | 482 (464–498) | 0.54 |
Mean follow-up time (range, months) | 27 (24–36) | 32 (24–42) |
p<0.05 (statistically significant).
BCVA, best corrected distance and near visual acuity; CNV, choroidal neovascularisation; ETDRS, Early Treatment Diabetic Retinopathy Study; logRAD, logarithm of reading acuity determination; LP, light perception; NRA, no reading ability; RPE, retinal pigment epithelium; RT, retinal thickness; TX, transplantation.