Table 2

Predictors of fibrosis of the retina in 52 diabetes patients

VariableContrastDegree of fibrosis
OR (95% CI)p Value
Univariate ordinal regression
 CTGFPer unit increase1.38 (1.19 to 1.61)<0.001
 VEGFPer 10-fold increase0.35 (0.19 to 0.67)0.001
 Ratio CTGF/log10(VEGF)Per unit increase1.27 (1.12 to 1.43)<0.001
Multiple ordinal regression*
 CTGFPer unit increase1.37 (1.16 to 1.60)<0.001
 VEGFPer 10-fold increase0.37 (0.18 to 0.78)0.009
  • * CTGF and VEGF in model.

  • CTGF, connective tissue growth factor; VEGF, vascular endothelial growth factor.