Table 4

Multivariate regression analysis to assess the influence of each pretreatment factor on BCVA change at 2 and 3 years after intravitreal bevacizumab treatment

FactorBCVA change at 2 yearsBCVA change at 3 years
B95% CIβp ValueB95% CIβp Value
Baseline BCVA (No of ETDRS letters)−0.49−0.7 to −0.3−0.632<0.0001−0.49−0.8 to −0.2−0.5720.001
Age (years)−0.32−0.6 to −0.06−0.3380.019−0.39−0.7 to −0.1−0.4170.01
CNV location0.0940.6400.2440.231
Axial length (mm)−0.0450.745−0.2310.125
Baseline CNV area (mm2)−0.0220.883−0.1350.405
Peripapillary atrophy area (mm2)0.0270.861−0.2230.192
Adjusted R20.4520.418
  • β, standardised regression coefficient; adjusted R2, coefficient of multiple determination; B, non-standardised regression coefficient.

  • BCVA, best corrected visual acuity; CNV, choroidal neovascularisation; ETDRS, Early Treatment Diabetic Retinopathy Study.