Table 1

Total number of FG and Brn3a labelled RGCs per retina in non-dystrophic and dystrophic RCS rats at different postnatal days

MarkerNon-dystrophic RCSDystrophic RCS
FG
P365P540P365P450P540
RatLeftRightLeftRightLeftRightLeftRightLeftRight
181 02978 00274 14375 38069 75578 32380 48173 92142 40257 045
275 92277 75780 38273 65475 32969 00760 61268 33639 73654 304
379 03272 20276 98379 86072 89169 08772 45168 67260 89242 580
475 32681 20576 04769 04580 00781 41656 21752 624
570 83766 01060 61268 33661 54954 714
676 73265 55467 69562 50174 49466 754
767 25469 17455 12655 730
Mean±SD77 827±232377 291±323877 169±255076 298±261572 692±329969 457±389770 309±813470 530±588155 730±11 00054 735±6571
Mean±SD77 599±283076 733±261971 074±395670 420±709855 232±9074*†
MarkerNon-dystrophic RCSDystrophic RCS
Brn3a
P365P540P365P450P540
RatLeftRightLeftRightLeftRightLeftRightLeftRight
181 07479 84980 30580 19075 12974 31583 61979 59774 52459 893
280 60783 16578 25979 15877 45481 11871 32379 78871 52371 562
380 52378 89279 12678 95072 60569 63769 90578 51166 81969 345
478 22478 89278 56471 36879 78571 32368 87869 361
575 91582 19476 03776 93771 89569 384
681 53081 45676 65773 22877 74472 906
781 22378 39271 13470 838
Mean±SD80 107±110780 199±175679 230±83879 432±54277 488±300776 925±476376 221±468276 564±3.21771 788±330869 041±3937
Mean±SD80 153±146879 331±71377 207±399376 392±402070 414±3887*†
  • Number of RGCs quantified in each of the analysed retinas. The penultimate row shows the mean±SD of the left or right retinas. Because there were no differences among them, the last row shows the mean±SD of both retinas for each group.

  • *Statistically significant compared with control and previous postnatal times (Kruskal–Wallis test).

  • †Statistically significant when comparing between markers at the same postnatal time (Mann–Whitney test).

  • FG, Fluorogold; RCS, Royal College of Surgeons; RGC, retinal ganglion cell.