The power value of SNPs with VKH syndrome
| Chr | SNP | Allele | Stage | MAF (Case/control) | OR | Power |
|---|---|---|---|---|---|---|
| 1 | rs77258390 | A | Chinese Singaporean | 18.8/3.7 | 5.9 | 0.94 |
| rs3762318 | C | 20.3/4.8 | 5.0 | 0.93 | ||
| rs78597810 | C | 18.8/3.7 | 5.9 | 0.94 | ||
| rs12568393 | A | 18.8/3.7 | 5.9 | 0.94 | ||
| rs12561798 | C | 18.8/3.7 | 5.9 | 0.94 | ||
| rs76436269 | A | 18.8/3.7 | 5.9 | 0.94 | ||
| rs78377598 | T | 18.8/5.3 | 4.1 | 0.85 | ||
| rs117633859 | G | 21.7/5.9 | 4.4 | 0.92 | ||
| rs1884444 | G | 43.8/30.3 | 1.7 | 0.42 | ||
| 10 | rs10995276 | A | Thai | 34.6/18.2 | 2.3 | 0.67 |
| rs442309 | T | 17.9/7.6 | 2.6 | 0.53 | ||
| rs224048 | T | 34.6/18.2 | 2.3 | 0.67 | ||
| rs224052 | A | 34.6/18.2 | 2.3 | 0.67 | ||
| rs224057 | A | 34.6/18.2 | 2.3 | 0.67 | ||
| rs224058 | T | 34.6/18.2 | 2.3 | 0.67 | ||
| rs10995307 | C | 32.7/25.8 | 1.4 | 0.18 |
Power: we examined the power calculation using the Quanto program and assumed that the prevalence of VKH syndrome in Asian population is 0.001% according to the literature.
MAF, frequency of minor allele; SNP, single nucleotide polymorphism; VKH, Vogt–Koyanagi–Harada.