Bacteriological resolution (for Cagle-regrouped microbes and global) in the worse eye on day 7 (MFAS)
| Azithromycin (N=102) | Tobramycin (N=101) | ||||
|---|---|---|---|---|---|
| Cagle's category | Day 0 | Day 7 | Day 0 | Day 7 | |
| Gram-positive | |||||
| Staphylococcus aureus | II | 18 (17.6) | 15/16 (93.8) | 18 (17.8) | 12/16 (75.0) |
| Staphylococcus epidermis | III | 9 (8.8) | 8/8 (100.0) | 14 (13.9) | 12/12 (100.0) |
| Coagulase-negative Staphylococcus (others) | III | 14 (13.7) | 12/13 (92.3) | 12 (11.9) | 12/12 (100.0) |
| Streptococcus pneumoniae | I | 19 (18.6) | 13/17 (76.5) | 11 (10.9) | 7/11 (63.6) |
| Streptococcus Group A | I | 1 (1.0) | 1/1 (100.0) | 2 (2.0) | 2/2 (100.0) |
| Streptococcus viridans or alpha haemolytic | III | 7 (6.9) | 5/5 (100) | 6 (5.9) | 4/5 (80.0) |
| Streptococcus (others) | II | 2 (2.0) | 1/1 (100.0) | 2 (2.0) | 1/2 (50.0) |
| Micrococcus luteus/Stomatococcus mucilaginosus | III | 1 (1.0) | 1/1 (100.0) | – | – |
| Corynebacterium | IV | 1 (1.0) | 1/1 (100.0) | 1 (1.0) | 1/1 (100.0) |
| Gram-negative | |||||
| Neisseria | I | 1 (1.0) | 1/1 (100.0) | 2 (2.0) | 2/2 (100.0) |
| Branhamella catarrhallis | II | 3 (2.9) | 1/1 (100.0) | – | – |
| Haemophilus | I | 28 (27.5) | 23/25 (92.0) | 36 (35.6) | 33/35 (94.3) |
| Pseudomonas | I | 2 (2.0) | 2/2 (100.0) | 5 (5.0) | 4/5 (80.0) |
| Acinetobacter | I | 2 (2.0) | 1/1 (100.0) | – | – |
| Enterobacteriaceae | I | 8 (7.8) | 6/7 (85.7) | 5 (5.0) | 5/5 (100.0) |
| Gram-negative rods (other) | I | 1 (1.0) | 1/1 (100.0) | – | – |
| Global* | 79/88 (89.8) | 82/94 (87.2) | |||
Data are frequency (%): patient(s) with bacterial resolution/patient(s) with positive pathogenic status on day 0 (%).
*Between-group difference not significantly different (p=0.679; CMH test).
CMH, Cochran–Mantel–Haenszel; MFAS, microbiologically positive full analysis set.