Table 1

Mean choroidal thickness in pretreated and treatment-naive patients prior to and after a loading dose of three 2 mg aflibercept injections at 4 weeks interval

Retinal areaPretreated patients mean choroidal thicknessTreatment-naive patients mean choroidal thickness
BeforeAfterp ValueBeforeAfterp Value
2500NCT112.4±49.7104.8±49.4<0.001125.3±52.1110.0±41.2<0.001
300NCT173.7±58.2164.9±56.8<0.001218.7±69.2196.3±71.2<0.001
SFCT182.8±57.4172± 57.7<0.001226.4±68.5208.0±66.6<0.001
300TCT173.6±57.5163.7±56.2<0.001225.7±71.1209.3±68.8<0.001
2500TCT176.2±55.1165.5±54.6<0.001213.9±71.3195.7±78.5<0.001
  • 2500NCT=choroidal thickness 2500 µm nasal from the central fovea, 300NCT=choroidal thickness 300 µm nasal from the central fovea, SFCT=subfoveal choroidal thickness, 300TCT=choroidal thickness 300 µm temporal from the central fovea, 2500TCT=choroidal thickness 2500 µm temporal from the central fovea.

  • Data presented as mean±SD.