Mean choroidal thickness in untreated fellow eyes of pretreated and treatment-naive patients prior to and after a loading dose of three 2 mg aflibercept injections at 4 weeks interval
| Retinal area | Fellow eye—pretreated choroidal thickness (n=31) | Fellow eye—treatment-naive choroidal thickness (n=17) | ||||||
|---|---|---|---|---|---|---|---|---|
| Before | After | Change | p Value | Before | After | Change | p Value | |
| 2500NCT | 131.5±49.2 | 130.0±49.8 | 1.5±4.6 | 0.082 | 123.3±63.7 | 117.5±62.7 | 5.8±7.6 | 0.007 |
| 300NCT | 195.5±47 | 193.7±48.0 | 1.7±4.7 | 0.051 | 216.6±81.8 | 209.3±83.7 | 7.3±9.2 | 0.002 |
| SFCT | 198.4±45.8 | 198.7±45.7 | −0.3±3.9 | 0.645 | 222.5±80.2 | 218.5±82.7 | 4.0±11.9 | 0.067 |
| 300TCT | 197.7±43.7 | 196.5±45.1 | 1.2±4.3 | 0.126 | 224.6±81.0 | 219.6±81.6 | 5.1±10.1 | 0.006 |
| 2500TCT | 200.5±42.3 | 200.0±42.3 | 0.5±3.2 | 0.404 | 222.0±73.6 | 219.3±74.4 | 2.7±2.6 | 0.002 |
2500NCT=choroidal thickness 2500 µm nasal from the central fovea, 300NCT=choroidal thickness 300 µm nasal from the central fovea, SFCT=subfoveal choroidal thickness, 300TCT=choroidal thickness 300 µm temporal from the central fovea, 2500TCT=choroidal thickness 2500 µm temporal from the central fovea.
Data presented as mean±SD.