Clinical summary of 12 patients with BrightOcular iris implant
| Case number-country of implantation | Age | Gender | Race | Uveitis | Glaucoma | Corneal decompensation | Explantation months after implant | Subsequent surgeries | Vision |
|---|---|---|---|---|---|---|---|---|---|
| 1-Tunisia | 40 | F | C | Yes OU (resolved after explantation) | Yes OD 42 mm Hg, OS 10 mm Hg on Rx; peripheral anterior synechiae 300° OD and 270° OS | Yes OD: endothelial cell count 1197/mm2 OD, 2372/mm2 OS | Yes after 5 months | Planned filtration OD | Initial 6/24 OD 6/6 OS; final 6/6 OU |
| 2-Lebanon | 39 | F | C | Yes OU uncontrolled despite three monthly subtenon corticosteroid injections | No | No | No (patient refused) | No | 6/6 OU |
| 3-Turkey | 25 | F | C | Yes OU | Yes OU 35 mm Hg | Yes OU with corneal neovascularisation OU | Yes after 12 months | No | 6/30 OU normalised subsequently OU |
| 4-Tunisia | 24 | M | C | Yes (started 6 months after implantation; recurred 2 months after explantation) | No | No | Yes after 12 months | No | 6/6 OU |
| 5-Lebanon | 35 | F | C | Yes OU | No | Yes OD | Yes after 1 month | No | 6/6 OU |
| 6-Tunisia | 38 | F | C | No | No | No (patient advised) | No | 6/6 OU | |
| 7-Lebanon | 25 | F | C | Yes OU | Yes 55 mm Hg OD 62 mm Hg OS (not respond to medical therapy; no PI) | Yes | No (patient advised) | No | CF 2 m OD; 20/400 OS |
| 8-Lebanon | 26 | F | C | Yes OU | Yes 48 mm Hg OD 50 mm Hg OS (not respond to medical therapy; no PI) | Yes | No (patient advised) | No | CF 4 m OD; 20/400 OS |
| 9-Jordan | 32 | F | C | Yes OU | Yes | Yes | Yes after 24 months | No | 6/12 OD; 6/6 OS |
| 10-Jordan | 25 | F | C | No | No | No | Yes after 18 months | No | 6/6 OU |
| 11-Turkey | 38 | F | A | Yes OU | No | No | Yes after 12 months | No | 6/6 OU |
| 12-Tunisia | 33 | F | A | Yes OU | Yes | No | Yes after 12 months | No | 6/6 OU |
Cases 5 and 6 were partly mentioned previously.14 ,15
C, Caucasian; CF, counting fingers; F, female; M, male; OD, right eye; OS, left eye; OU, bilateral; PI, peripheral iridotomy; Rx, therapy.