Summary of description of study population by glaucoma status
| Patient characteristics | n | Glaucoma (n=46) | No glaucoma (n=564) | Overall (n=610) |
|---|---|---|---|---|
| Baseline | ||||
| Drug (Avastin) | 610 | 23 (50.0%) | 273 (48.4%) | 296 (48.5%) |
| Age (years) | 610 | 80.0 (7.1) | 77.5 (7.4) | 77.7 (7.4) |
| 50–69 | 2 (4.3%) | 90 (16.0%) | 92 (15.1%) | |
| 70–74 | 13 (28.3%) | 97 (17.2%) | 110 (18.0%) | |
| 75–79 | 8 (17.4%) | 151 (26.8%) | 159 (26.1%) | |
| 80–84 | 7 (15.2%) | 132 (23.4%) | 139 (22.8%) | |
| 85+ | 16 (34.8%) | 94 (16.7%) | 110 (18.0%) | |
| Gender (male) | 610 | 18 (39.1%) | 226 (40.1%) | 244 (40.0%) |
| Preinjection IOP in study eye | 607 | 16.8 (3.8) | 15.3 (3.1) | 15.4 (3.2) |
| Postinjection IOP change in study eye | 594 | 2.8 (6.5) | 3.1 (5.6) | 3.1 (5.7) |
| Preinjection IOP eye difference (study eye IOP minus fellow eye IOP) | 606 | −0.7 (3.8) | 0.0 (1.6) | −0.1 (1.9) |
| During the trial | ||||
| Any cataract surgery (pseudo/aphakic) | 610 | 27 (58.7%) | 192 (34.0%) | 219 (35.9%) |
| In study eye only | 7 (25.9%) | 39 (20.3%) | 46 (21.0%) | |
| In fellow eye only | 3 (11.1%) | 29 (15.1%) | 32 (14.6%) | |
| In both eyes | 17 (63.0%) | 124 (64.6%) | 141 (64.4%) | |
| Months in trial | 610 | 23.5 (23.0 to 24.5) | 23.6 (22.8 to 24.3) | 23.6 (22.8 to 24.3) |
| Months between injections | 13 371 | 1.0 (0.9 to 1.8) | 1.0 (0.9 to 1.2) | 1.0 (0.9 to 1.2) |
| Time (min) between injection and postinjection IOP measurement | 9966 | 25 (15 to 33) | 21 (12 to 32) | 22 (13 to 32) |
| Mean arterial pressure (mm Hg) | 4795 | 95.4 (10.6) | 96.3 (10.9) | 96.2 (10.9) |
| Preinjection IOP in study eye | 13 281 | 16.6 (4.0) | 15.3 (3.3) | 15.4 (3.4) |
| Postinjection IOP change in study eye | 10 009 | 4.4 (6.9) | 3.8 (5.3) | 3.8 (5.4) |
| Preinjection IOP eye difference (study eye IOP minus fellow eye IOP) | 13, 208 | −0.4 (5.0) | 0.1 (1.8) | 0.5 (2.3) |
| At visit 24 | ||||
| Preinjection IOP in study eye | 514 | 17.0 (4.0) | 15.7 (3.3) | 15.8 (3.4) |
| Postinjection IOP change in study eye (at visit 23) | 358 | 5.1 (4.1) | 3.9 (5.1) | 4.0 (5.0) |
| Preinjection IOP eye difference (study eye IOP minus fellow eye IOP) | 510 | 0.5 (2.2) | 0.2 (1.9) | 0.2 (1.9) |
IOP, intraocular pressure.