Class: PARASYMPATHOMIMETICS (CHOLINERGIC DRUGS)
| Compound | Mode of action | IOP reduction | Contra-indications | Side effects | |
|---|---|---|---|---|---|
| Oral | Glycerol Isosorbide Alcohol | Dehydration and reduction in vitreous volume Posterior movement of the iris-lens plane with deepening of the AC | 15-20% | Cardiac or renal failure | Nausea, Vomiting, dehydration (special caution in diabetic patients). Increased diuresis, hyponatremia when severe may lead to lethargy, obtundation, seizure, coma. Possible increase of bood glucose. Acute oliguric renal failure. Hypersensitivity reaction |
| Intravenous | Mannitol Urea | 15-30% |