Table 2

Baseline demographics and disease characteristics by baseline DRSS score

Low risk (≤43)
n=301
Moderate risk (47)
n=153
High risk (≥53)
n=294
LaserIntravitreal afliberceptLaserIntravitreal afliberceptLaserIntravitreal aflibercept
Age, years64.9 (7.7)64.9 (9.2)63.7 (8.3)63.8 (8.9)59.4 (9.2)60.0 (9.6)
Duration of diabetes, years18.5 (9.7)18.3 (11.2)16.5 (10.0)16.3 (9.4)14.3 (9.2)13.5 (8.9)
HbA1c, %7.40 (1.2)7.86 (1.5)7.71 (1.4)7.75 (1.7)7.83 (1.9)7.83 (1.5)
BCVA, ETDRS letters60.6 (10.8)60.5 (9.7)62.3 (9.6)62.4 (9.6)58.5 (11.7)57.2 (11.5)
CRT, µm487 (141.2)472.3 (136.1)488.6 (149.5)469.3 (122.0)541.4 (168.3)535.2 (177.3)
  • Data presented as mean (SD).

  • Only those with gradable baseline DRSS score are included.

  • BCVA, best-corrected visual acuity; CRT, central retinal thickness; DRSS, Diabetic Retinopathy Severity Scale; ETRDS, Early Treatment Diabetic Retinopathy Study; HbA1c, glycated haemoglobin A1c.