Table 3

Association of early age-related macular degeneration with SNPs

GeneSNP1 vs 0 copy of minor allele2 vs 0 copies of minor alleleAdditive per allele
OR*95% CIPOR*95% CIPOR*95% CIP
TLR3rs37752911.010.86 to 1.200.8681.130.83 to 1.540.4251.040.92 to 1.160.520
LOC107986598rs47117510.950.78 to 1.140.5580.910.69 to 1.200.5020.950.84 to 1.080.452
FRKrs19999300.830.66 to 1.050.1171.630.39 to 6.770.4980.880.69 to 1.120.285
ABCA1rs18830250.960.79 to 1.170.6980.960.77 to 1.190.7260.980.88 to 1.090.699
LIPCrs104680170.970.82 to 1.140.6771.080.67 to 1.750.7440.990.85 to 1.150.913
CETPrs37642611.080.91 to 1.280.3651.100.90 to 1.330.3391.060.96 to 1.170.228
APOErs4293580.930.77 to 1.120.4540.800.35 to 1.840.5940.930.77 to 1.100.380
APOErs74120.970.74 to 1.270.8261.380.42 to 4.550.5941.000.79 to 1.270.994
CFDrs38269451.020.88 to 1.200.7581.100.87 to 1.390.3991.040.94 to 1.150.416
  • *Adjusted for age, sex and centre.

  • SNP, single nucleotide polymorphism.